Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species

نویسندگان

  • Petur W. Dalsgaard
  • Bent O. Petersen
  • Jens Ø. Duus
  • Christian Zidorn
  • Jens C. Frisvad
  • Carsten Christophersen
  • Thomas O. Larsen
چکیده

Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2012